李健，1970年9月22日出生、教授、博士研究生导师。2005年毕业于北京中医药大学中西医结合基础专业获博士学位，是教育部“创新团队”及“创新引智基地”中方骨干成员。2009,1~2010,1在加拿大McMaster大学医学院分子病理系从事博士后研究工作；2016,2~2017,2获国家留学基金委员会“青年骨干计划”基金资助赴美国亚特兰大Morehouse School of Medicine研修学习。现任“组织学与胚胎学”课程负责人、教研室主任。

　　教学工作：主讲本科（包括长年制）“组织学与胚胎学”、《现代医学基础概论I》；主讲或参与研究生《医学科研思路方法与程序》、《分子细胞学与疾病》、《临床病理生理学》等课程。

　　研究领域：（1）中医药防治肝病（脂肪肝、脂肪性肝炎、肝纤维化）的作用机制；（2）有毒中药“毒/效”相关的机制；（3）保肝中药及单体化合物抗氧化及抗炎的分子机制。

　　基金项目：（1）国家自然科学基金面上项目：从“有故无殒”理论探究自噬在雷公藤肝脏毒性中的作用及机制（No. 81873099），2019.1-2022.12，在研；（2）国家自然科学基金面上项目：从FXR/PXR/CYP3A4信号通路探讨雷公藤诱发胆汁淤积性肝损伤的分子机制（No. 81273884）,2012.1-2016.12，已结题。

　　主要代表作：

　　1. Can Xu1†, Caidan Rezeng†, Jian Li†, Lan Zhang, Yujing Yan, Jian Gao,Yingfeng Wang, Zhongfeng Li and Jianxin Chen. 1H NMR-Based Metabolomics Study of the Toxicological Effects in Rats Induced by “Renqing Mangjue” Pill, a Traditional Tibetan Medicine.Front. Pharmacol. 8:602. doi: 3389/fphar.2017.00602 （同等贡献第一作者）

　　2. Song Yang, Hefang Xu, Baosheng Zhao, Shasha Li, Tingting Li, Xinfang Xu, Tianjiao Zhang, Ruichao Lin, Jian Li†, and Xiangri Li†. The Difference of Chemical Components and Biological Activities of the Crude Products and the Salt-Processed Product from Semen Cuscutae. Evidence-based Complementary and Alternative Medicine. 2016, ID8656740 （共同通讯）

　　3. Ge Wang, Zehao Li, Hao Li, Lidan Li, Jian Li† and Changyuan Yu† Metabolic Profile Changes of CCl4-Liver Fibrosis and Inhibitory Effects of Jiaqi Ganxian Granule. Molecules.2016, 21, 698:1-19（共同通讯）

　　4. Jian Li, Zezhou Liu, Mingxing Guo, Kejia Xu, Miao Jiang, Aiping Lu, and Xiaoyan Gao. Metabolomics Profiling to Investigate the Pharmacologic Mechanisms of Berberine for the Treatment of High-Fat Diet-Induced Nonalcoholic Steatohepatitis. Evidence-based Complementary and Alternative Medicine. 2015, doi:10.1155/2015/897914

　　5. Yunliang Wang†, Jian Li†, Li Zhuge, Dongwei Su, Meijuan Yang, Shiying Tao, Junxiang Li. Comparison between the efficacies of curcumin and puerarin in C57BL/6 mice with steatohipatisis induced by a methionine-and choline-deficient diet. Experimental and Therapeutic Medicine, 2014, 7: 663-668.（同等贡献）

　　6. Xiaoyan Gao, Mingxing Guo, Qiang Li, Long Peng, Haiyu Liu, Li Zhang, Xu Bai, Yingxin Wang, Jian Li†, Chengke Cai†. Plasma metabolomics profiling to reveal antipyretic mechanism of Shuang-Huang-Lian injection on Yeast-induced pyrexia rats. PLOS ONE, 2014, 9(6): 100017. （共同通讯）

　　7. Yong Tan†, Jian Li†, Xinru Liu†, Joshua KO, Xiaojuan He, Cheng Lu, Zhengli Liu, Hongyan Zhao, Cheng Xiao, Xuyan Niu, Qinglin Zha, Zhiling Yu, Weidong Zhang, and Aiping Lu, Deciphering the Differential Toxic Responses of Radix aconiti lateralis praeparata in Healthy and Hydrocortisone-Pretreated Rats Based on Serum Metabolic Profiles. 2012, JPR 10.0.1465（同等贡献）

　　8. Jian Li†, Run-guo Wu†, Fan-yun Meng†, Zhong Wang, Chang-ming Wang, Yong-yan Wang, Zhan-jun Zhang. Synergism and rules from combination of Baicalin, Jasminoidin and Desoxycholic acid in refined Qing Kai Ling for treat ischemic stroke mice model. PLOS ONE, 2012,7(9):e45811.（同等贡献）

　　9. Jian Li, Cheng Lu, Miao Jiang, Xuyan Niu, Hongtao Guo, Li Li, Zhaoxiang Bian, Na Lin, and iping Lu. Traditional ChineseMedicine-Based Network Pharmacology Could Lead to NewMulticompound Drug Discovery. Evidence-based Complementary and Alternative Medicine. 2012. Doi: 10.1155/2012/149762

　　10. Cheng Xiao†, Jian Li†, Xinxin Dong, Xiaojuan He, Xuyan Niu, Cha Liu, Guoyue Zhong, Rudolf Bauer, Dajian Yang, Aiping Lu. Anti-oxidative and TNF-α suppressive activities of puerarin derivative (4AC) in RAW264.7 cells and collagen-induced arthritic rats. European Journal of Pharmacology. 2011,666:242-250（同等贡献）

　　11. Jian Li, Yongheng Lu, Cheng Xiao, Cheng Lu, Xuyan Niu, Xiaojuan He, Hongyan Zhao, Yong Tan, Aiping Lu. Comparision of toxic reaction of Tripterygium wilfordii multiglycoside in normal and adjuvant arthritic rats. Journal of Ethnopharmacology. 2011；135：270-277