（一）科研项目
国家自然科学基金面上项目：从信号转导网络调控角度揭示三七、栀子组分配伍发挥血管保护作用的分子机制（编号81273885）
国家自然科学基金面上课题：羟基红花黄色素A抗肿瘤血管生成及对MARK信号转导通路的影响（编号30572436）
国家自然科学基金面上项目：基于SELEX方法的研究栀子苷及其与三七总皂苷配伍防治AD的多靶点协同作用机制（编号81473546）
国家自然科学基金面上项目：栀子、三七有效组分对AD转基因动物突触功能重建的影响及其配伍机制（编号81072901）
国家自然科学基金青年基金项目：运用解毒通络法从炎症论治阿尔茨海默病的病理基础（编号30500682）
国家自然科学基金青年基金项目：基于NADPH氧化酶活性调控的益心解毒方治疗心力衰竭的机制研究（编号81102839）
国家自然科学基金青年基金项目：基于Notch信号通路抑制的脾虚证食欲中枢机制研究（编号81603514）
国家自然科学基金基金项目：从c-kit信号探讨温肾润肠法的分子机制（编号:30600799）
重大新药创制专项：芪参颗粒治疗冠心病心功能不全的临床前研究
教育部课题：三七总皂苷、栀子苷配伍促进AD 转基因小鼠突触功能重建的研究（编号20120013110013）
北京市自然基金：基于特征选择的气虚血瘀证（心肌缺血）生物学基础研究（编号7112077）
（二）科研成果
国家科技进步二等奖1人次
教育部科技进步一等奖1人次
教育部科技进步二等奖3人次
北京市科学技术二等奖1人次
北京市科学技术三等奖1人次
中华中医药学会李时珍医药创新奖1人次
中华中医药学会科学技术三等奖1人次
第11届北京青年科技优秀论文一等奖1人次
北京中医药大学自然科学二等奖3次
（三）发表论文及论著
1.Critical residues and motifs for homodimerization of the first transmembrane domain of the plasma membrane glycoprotein CD36. 2017. J. Biol. Chem. 292, 8683-8693
2.BCL6 mediates the effects of Gastrodin on promoting M2-like macrophage polarization and protecting against oxidative stress-induced apoptosis and cell death in macrophages. 2017. Biochemical and Biophysical Research Communications. 486, 458-464
3.In Vitro Selection of DNA Aptamers that Binds Geniposide. 2017. Molecules. 22, 383
4.Systems-biology dissection of mechanisms and chemical basis of herbal formula in treating chronic myocardial ischemia. 2016. Pharmacol. Res. 114, 196-208
5.The prescriptions from Shenghui soup enhanced neurite growth and GAP-43 expression level in PC12 cells. 2017. BMC Complement Altern Med. 16, e0131266
6.Geniposide attenuates inflammatory response by suppressing P2Y14 receptor and downstream ERK1/2 signaling pathway in oxygen and glucose deprivation-induced brain microvascular endothelial cells. 2016. Journal of Ethnopharmacology. 185, 77-86
7.Molecular mechanism of inhibition of the abnormal proliferation of human umbilical vein endothelial cells by hydroxysafflor-yellow A. 2016. Pharmaceutical Biology. 54, 1800-1807
8.Anti-Alzheimer Therapeutic Drugs Targeting γ-Secretase. 2016. Curr Top Med Chem. 16, 549-557
9.Integration of inhibition kinetics and molecular dynamics simulations to determine the effects of Zn2+ on acetaldehyde dehydrogenase 1. 2015. Process Biochemistry. 50, 1878-1884
10.Glytan decreases portal pressure via mesentery vasoconstriction in portal hypertensive rats. 2014. WJG. 20, 16674-16682
11.Effects of hydroxysafflor yellow A on ALDH1: Inhibition kinetics and molecular dynamics simulation. 2014. Process Biochemistry. 49, 1664-1672
12.Response gene to complement 32 (RGC-32) in endothelial cells is induced by glucose and helpful to maintain glucose homeostasis. 2014. International Journal of Clinical and Experimental Medicine. 7, 2541-2549
13.Effect of Ca2+ on the activity and structure of α-glucosidase: inhibition kinetics and molecular dynamics simulations. 2014. Journal of Bioscience and Bioengineering. 117, 696-705
14.Role of A20 in cIAP-2 protection against tumor necrosis factor α (TNF-α)-mediated apoptosis in endothelial cells. 2014. IJMS. 15, 3816-3833
15.Effect of Tongluojiunao injection made from Sanqi (Radix Notoginseng) and Zhizi (Fructus Gardeniae) on brain microvascular endothelial cells and astrocytes in an in vitro ischemic model. 2014. Journal of Traditional Chinese Medicine. 34, 725-732
16.A Chinese medicine preparation induces neuroprotection by regulating paracrine signaling of brain microvascular endothelial cells. 2014. Journal of Ethnopharmacology. 151, 686-693
17.The protective effect of geniposide on human neuroblastoma cells in the presence of formaldehyde. 2013. BMC Complement Altern Med. 13, 152
18.A New Biomarkers Feature Pattern Consisting of TNF-α, IL-10, and IL-8 for Blood Stasis Syndrome with Myocardial Ischemia. 2013. Evidence-Based Complementary and Alternative Medicine. 2013, 130702-8
19.Neuroprotective effects of TongLuoJiuNao in neurons exposed to oxygen and glucose deprivation. 2010. Neuroscience Research. 68, e454
20.The impact of paracrine signaling in brain microvascular endothelial cells on the survival of neurons. 2009. Brain Research. 1287, 28-38